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cxcl 10  (R&D Systems)


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    R&D Systems cxcl 10
    Cxcl 10, supplied by R&D Systems, used in various techniques. Bioz Stars score: 93/100, based on 39 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
    https://www.bioz.com/result/cxcl 10/product/R&D Systems
    Average 93 stars, based on 39 article reviews
    cxcl 10 - by Bioz Stars, 2026-03
    93/100 stars

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    Cytokines in cell-free culture supernatants of senescent hepatocytes. (A) Representative images of cytokine arrays. 1, CCL-2; 2, CXCL-1; 3, CXCL-10. (B) Bar graph representing the densitometry of the spotted antibody array results. The secretion of IL-1α, IL-1β, IL-6, CCL-2, CXCL-1 and CXCL-2 was differentially increased. (C) ELISA analysis of CXCL-9, −10 and −11. The levels of only CXCL-10 exhibited significant augmentation. n=5. Data were analyzed by Student's t-test. **P<0.01. IL, interleukin; CCL, C-C motif chemokine ligand; CXCL, C-X-C motif chemokine ligand.

    Journal: Experimental and Therapeutic Medicine

    Article Title: Senescent hepatocytes enhance natural killer cell activity via the CXCL-10/CXCR3 axis

    doi: 10.3892/etm.2019.8037

    Figure Lengend Snippet: Cytokines in cell-free culture supernatants of senescent hepatocytes. (A) Representative images of cytokine arrays. 1, CCL-2; 2, CXCL-1; 3, CXCL-10. (B) Bar graph representing the densitometry of the spotted antibody array results. The secretion of IL-1α, IL-1β, IL-6, CCL-2, CXCL-1 and CXCL-2 was differentially increased. (C) ELISA analysis of CXCL-9, −10 and −11. The levels of only CXCL-10 exhibited significant augmentation. n=5. Data were analyzed by Student's t-test. **P<0.01. IL, interleukin; CCL, C-C motif chemokine ligand; CXCL, C-X-C motif chemokine ligand.

    Article Snippet: Alternatively, DMEM/F12/10% FBS containing recombinant CXCL-10 (10 ng/ml; R&D Systems, Inc.) was chosen as the positive control.

    Techniques: Ab Array, Enzyme-linked Immunosorbent Assay

    Migration of NK cells in response to supernatants from senescent AML12 cells. Anti-CXCR3 or anti-CXCL-10 antibodies were used for the blocking assay. The percentage of NK cell migration was calculated by dividing the number of cells that migrated to the lower well by the total number of cells. n=3. Data were analyzed by one-way ANOVA with Tukey's post hoc test. ***P<0.001. NK, natural killer; CXCR, C-X-C motif chemokine receptor; CXCL, C-X-C motif chemokine ligand.

    Journal: Experimental and Therapeutic Medicine

    Article Title: Senescent hepatocytes enhance natural killer cell activity via the CXCL-10/CXCR3 axis

    doi: 10.3892/etm.2019.8037

    Figure Lengend Snippet: Migration of NK cells in response to supernatants from senescent AML12 cells. Anti-CXCR3 or anti-CXCL-10 antibodies were used for the blocking assay. The percentage of NK cell migration was calculated by dividing the number of cells that migrated to the lower well by the total number of cells. n=3. Data were analyzed by one-way ANOVA with Tukey's post hoc test. ***P<0.001. NK, natural killer; CXCR, C-X-C motif chemokine receptor; CXCL, C-X-C motif chemokine ligand.

    Article Snippet: Alternatively, DMEM/F12/10% FBS containing recombinant CXCL-10 (10 ng/ml; R&D Systems, Inc.) was chosen as the positive control.

    Techniques: Migration, Blocking Assay